[Clinical research of primary hyperparathyroidism]

To investigate the clinical features and therapeutic procedures of primary hyperparathyroidism(PHPT) in China.

Clinical data of twenty eight consecutive in-patients with PHPT hospitalized in the Second Hospital Affiliated to Zhejiang University Medical School during the period 1968-2001 were analyzed retrospectively and compared with the domestic relevant literature.

Twenty-eight patients underwent operative treatment, including exploratory operation of neck in 14 cases, cystectomy in one case, cancer radical operation in one case, and direct parathyroid adenomectomy in 14 cases with solitary adenoma. All cases resulted in normocalcemia after operation. The cure rate of PHPT was 100%. No early and long-term operative complications and recurrence were found.

PHPT, mostly occurring among people aged 30-40, is rare in China. Osteopathy can be seen in 90% of PHPT patients. For solitary parathyroid adenoma, direct adenomectomy through small neck incision is a safe and effective alternative to conventional neck exploratory operation.