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Using baseline and recombinant human TSH-stimulated Tg measurements to manage thyroid cancer without diagnostic

Leonard Wartofsky

    The Journal of Clinical Endocrinology and Metabolism
    |April 5, 2002
    PubMed
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    Goiter refers to an abnormal enlargement of the thyroid gland that may appear as a diffuse goiter (uniform enlargement) or nodular (single or multiple nodules). Functionally, it is classified as nontoxic (normal/low hormone levels) or toxic (excess hormone production).PathophysiologyDiffuse thyroid enlargement typically results from prolonged stimulation by thyroid-stimulating hormone (TSH) or TSH-like agents, commonly seen in hypothyroidism or iodine deficiency. In contrast, in hyperthyroid...