Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Limb deformities and three-dimensional ultrasound.

Milan Kos1, Tomislav Hafner, Biserka Funduk-Kurjak

  • 1Medical School University of Zagreb, Department of Obstetrics and Gynecology, Sveti Duh General Hospital, Zagreb, Croatia.

Journal of Perinatal Medicine
|April 6, 2002
PubMed
Summary

Three-dimensional (3D) ultrasonography significantly improves antenatal detection of fetal limb deformities. This advanced imaging technique aids in diagnosing conditions like clubfoot and polydactyly, offering better visualization of unborn babies.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Respiratory-onset peripartum cardiomyopathy: a systematic review of diagnostic pitfalls and clinical outcomes.

Journal of perinatal medicine·2026
Same author

Inflammasome biology in preeclampsia: from Bnip3-mitophagy to Nlrp1-driven placental injury - a systematic review and translational roadmap.

Journal of perinatal medicine·2026
Same author

Blood-based predictive biomarkers for preterm birth: Redefining risk stratification in modern perinatal care.

Tzu chi medical journal·2026
Same author

Mental health in the perinatal period: bridging the gaps in care, evidence, and policy.

Journal of perinatal medicine·2026
Same author

Reimagining Placental Perfusion in Preeclampsia: Integrating Doppler Ultrasound, Three-dimensional Vascular Indices, and Predictive Artificial Intelligence.

Journal of medical ultrasound·2026
Same author

Immunoediting in pregnancy: a new paradigm for understanding fetal tolerance and obstetric disease.

Journal of perinatal medicine·2026

Area of Science:

  • Medical Imaging
  • Fetal Medicine
  • Orthopedics

Background:

  • Antenatal detection of fetal limb deformities is crucial for timely intervention.
  • Two-dimensional (2D) sonography has limitations in visualizing complex limb anomalies.
  • Advancements in ultrasound technology offer potential for improved diagnostic accuracy.

Purpose of the Study:

  • To evaluate the efficacy of three-dimensional (3D) ultrasonography in enhancing the antenatal diagnosis of fetal limb deformities.
  • To compare the diagnostic capabilities of 3D ultrasound with 2D ultrasound for limb anomaly detection.

Main Methods:

  • A cohort of 347 patients with suspected fetal extremity anomalies was studied.
  • Three-dimensional ultrasound devices (Combison 530D, Voluson 530D MT) were utilized for volume scanning.

Related Experiment Videos

  • Patients were scanned between 18-32 weeks of gestation.
  • Main Results:

    • Initial suspicion of limb abnormalities was noted in 41 of 347 patients via 2D sonography.
    • 3D sonography confirmed diagnoses in 28 of these cases, including clubfoot (17), polydactyly (3), contractures (3), and micromelia (4).
    • Normal anatomy was confirmed by 3D sonography in 13 of the 41 suspected cases.

    Conclusions:

    • Three-dimensional ultrasonography is highly effective for detecting isolated limb defects, developmental/positional deformations, and minor hand/foot anomalies.
    • Surface-mode and transparent-view reconstructions in 3D ultrasound provide superior visualization of fetal skeletal structures.
    • 3D sonography represents a significant advancement in the antenatal assessment of fetal limb development.