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[Colorectal spirochetosis, a possible but unusual cause of chronic diarrhea?]

G Macaigne, F David, J F Boivin

    Presse Medicale (Paris, France : 1983)
    |April 6, 2002
    PubMed
    Abstract

    Insights

    Human intestinal spirochetosis, a condition known since the late 1800s, can cause chronic diarrhea. Treatment with antibiotics resolved symptoms in one observed case, though its overall role in digestive disorders remains debated.

    Area of Science:

    • Gastroenterology
    • Microbiology
    • Infectious Diseases

    Background:

    • Human intestinal spirochetosis has been recognized for over a century.
    • Its prevalence in Western countries, based on biopsies, ranges from 2% to 7% in patients with digestive issues.
    • The exact pathogenic role of intestinal spirochetosis is currently under scientific debate.

    Observation:

    • A case of HIS presenting as chronic diarrhea is detailed.
    • Diagnosis was confirmed through colonic biopsies.
    • The patient's chronic diarrhea resolved following antibiotic therapy.

    Findings:

    • Antibiotic treatment was effective in resolving chronic diarrhea associated with intestinal spirochetosis in the presented case.
    • The pathogenic role of intestinal spirochetosis in digestive disorders is currently under scientific discussion.

    Implications:

    • This case highlights the potential efficacy of antibiotherapy for symptomatic intestinal spirochetosis.
    • Further research is warranted to clarify the controversial pathogenic role of HIS in various gastrointestinal conditions.

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