Effects of elements in human blood pressure control

Area of Science:

• Human Physiology
• Nutritional Biochemistry
• Environmental Health

Background:

• Human blood pressure regulation is a complex physiological process influenced by numerous factors.
• Historically, various elements have been implicated in cardiovascular health and blood pressure control.
• A comprehensive understanding of elemental influences on blood pressure is crucial for public health.

Purpose of the Study:

• To review and discuss the elements involved in human blood pressure control.
• To explore the historical and evolutionary context of elemental influences on blood pressure.
• To categorize elements based on their role in blood pressure regulation.

Main Methods:

• Conducted a literature search using MEDLINE and manual review of cited documents.
• Performed independent data extraction and cross-referencing of relevant studies.
• Analyzed and synthesized information on 28 known elements influencing blood pressure.

Main Results:

• Identified 15 elements significantly involved in human blood pressure regulation.
• Classified these elements into four groups: electrolyte (Na, K, Ca, Mg), metal (Zn, Cu, Fe), toxic (Pb, Hg, Cd, Ba, Tl, As), and miscellaneous (Li, Se).
• Discussed evolutionary data, mechanisms of action, and interactions among these elements.

Conclusions:

• Established the significance of 15 specific elements in regulating human blood pressure.
• Highlighted the public health importance of preventive control for toxic elements affecting blood pressure.
• Emphasized the need for ongoing research to further elucidate the influence of these elements.