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Updated: Aug 12, 2026

A Fibrin-Enriched and tPA-Sensitive Photothrombotic Stroke Model
Published on: June 4, 2021
Macular infarction in thrombotic thrombocytopenic purpura
1The Annette & Aron Rozin Department of Ophthalmology, Bnai Zion Medical Center & The Technion Faculty of Medicine, 47 Golomb Street, Haifa 31048, Israel.
Purpose:
To report a patient with transient acute generalized thrombotic thrombocytopenic purpura (TTP) who suffered severe permanent visual loss due to retinal vascular occlusions in both eyes.
Methods:
Case report.
Results:
Severe permanent visual loss occurred in a patient with acute transient TTP. Extensive soft exudates were seen at the fundus of both eyes. Fluorescein angiography demonstrated multiple retinal vascular occlusions associated with capillary nonperfusion.
Conclusions:
Severe and permanent visual loss due to retinal vascular occlusions demonstrated by fluorescein angiography occurred in a patient with transient thrombotic thrombocytopenic purpura.

