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Tuberculosis in Spain: epidemiological pattern and clinical practice.

M Diez1, C Huerta, T Moreno

  • 1Unidad de Investigación en Tuberculosis, Instituto de Salud Carlos III, Madrid, Spain. mdiez@isciii.es

The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease
|April 9, 2002
PubMed
Summary

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This summary is machine-generated.

Tuberculosis incidence in Spain was 38.5/100,000, with higher rates in men and specific age groups. Human immunodeficiency virus (HIV) infection was a key risk factor, influencing treatment strategies.

Area of Science:

  • Epidemiology
  • Infectious Diseases
  • Public Health

Background:

  • Tuberculosis (TB) remains a significant global health concern.
  • Understanding the epidemiological patterns and clinical practices of TB is crucial for effective control strategies.

Purpose of the Study:

  • To determine the incidence of all forms of tuberculosis (TB) in Spain.
  • To investigate the clinical practices associated with TB diagnosis and treatment.

Main Methods:

  • A comprehensive study was conducted across thirteen Autonomous Regions in Spain.
  • Data on TB cases diagnosed between May 1986 and April 1997 were collected through active surveillance and review of clinical records.

Main Results:

  • The overall TB incidence was 38.5/100,000, with smear-positive TB at 13.83/100,000.

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  • Higher incidence rates were observed in men and individuals aged 25-34 and 75+ years.
  • Human immunodeficiency virus (HIV) infection was identified as a major risk factor (17.7%), and microbiological confirmation rates varied between pulmonary and extra-pulmonary TB.

    • Conclusions:

    • The TB epidemiological profile in Spain differs from other industrialized nations, particularly in age distribution and prevalence of HIV infection.
    • Microbiological confirmation is more frequently achieved in pulmonary TB cases.
    • Treatment regimens, especially the use of four-drug therapy, were more common in HIV-positive patients.