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[Emerging parasitosis ans mycosis: risk and threats for the new millenium]
C Pinel1, R Grillot, P Ambroise-Thomas
1Service de parasitologie-mycologie, CHU Albert-Michallon, BP 217, 38043 Grenoble cedex 9, France.
Abstract:
For multiple reasons, the emergent infectious risks do not stop increasing these last twenty years. The climatic modifications and the human interventions modifying the biotope as well as the rapid spreading of resistant strains to treatments, generate re-emergence or emergence, all the more dramatic as the means of fight are reduced. These emergent or re-emergent diseases are extremely worrisome as their diagnosis and their prevention are often difficult. The important infesting power of parasites and the particularly effective capacities of adaptation of these eucaryotes contributed to the public health problems. Anthropozoonoses and zoonoses constitute a permanent risk the control of which is imaginary. The new pathogenic agents, the unusual clinical demonstrations in the context of deficiency of the host immune functions imply attentiveness and a permanent up to date of the knowledge of the biologist and of the different professionals of health. The risks with which are confronted the humanity during this century underline the necessity of determining mechanisms involved in the pathogenesis. The determination of the specific and vital biologic processes for the microorganism, could allow to define the most appropriated targets and the most effective and original means of fight.
Insights
Emerging infectious disease risks are rising due to climate change, human activity, and resistant strains. New pathogens and difficult diagnoses pose significant public health challenges, requiring updated knowledge for effective control.
Area of Science:
- Microbiology and Public Health
- Parasitology and Emerging Infectious Diseases
Context:
- Increasing global infectious disease risks over the past two decades.
- Climate change and human activities alter ecosystems, facilitating disease emergence.
- Spread of drug-resistant strains complicates treatment and control efforts.
Purpose:
- To highlight the growing threat of emergent and re-emergent infectious diseases.
- To emphasize the diagnostic and preventive challenges posed by these diseases.
- To underscore the need for understanding pathogen adaptation and pathogenesis.
Summary:
- Emergent infectious risks are escalating due to environmental changes and antimicrobial resistance.
- Parasitic infections and zoonotic diseases (anthropozoonoses and zoonoses) present ongoing public health concerns.
- Novel pathogens and atypical presentations in immunocompromised hosts demand vigilance and updated scientific knowledge.
Impact:
- Understanding pathogen biology is crucial for developing novel therapeutic targets and control strategies.
- Enhanced knowledge facilitates better preparedness against future infectious disease outbreaks.
- Addressing these risks requires interdisciplinary collaboration among biologists and healthcare professionals.