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Genital herpes simplex virus type 1 infection: new fields for an old acquaintance?
Lars Lippelt1, Rüdiger W Braun, Joachim E Kühn
1Institut für Medizinische Mikrobiologie, Abteilung Klinische Virologie, Universität Münster, Münster, Germany.
Intervirology
|April 9, 2002
Abstract:
Herpes simplex virus (HSV)-2 is the principal agent of chronic remittent genital herpes. Worldwide, only 10-20% of genital isolates are HSV-1. Studies from the British Isles and Scandinavia indicate, however, that HSV-1 is responsible for a significant proportion or even the majority of first clinical episodes of genital herpes in young women. Actual data show that a trend towards genital HSV-1 infections may also hold true for Germany. This article summarizes possible reasons for and consequences of the observed changes in the epidemiology of genital HSV infections.