Disseminated osteosarcoma arising in the pelvis after total hip arthroplasty

The development locally of a malignant neoplasm after total hip arthroplasty is rare but increasingly recognized. Its significance is unclear. The association could be fortuitous. If not, the rarity of the complication argues that constitutional factors are likely to be important in pathogenesis. We describe a case of disseminated osteosarcoma of the hip developing 6.5 years after total hip arthroplasty and review the related literature.