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[Urotoxic effect to intestinal bacteria in patients with chronic renal failure]
1Department of Nephrology, Xiangya Hospital, Hunan Medical University, Changsha 410008.
Abstract
Unlabelled:
To analyse the differences of intestinal bacterial quality and quantity, the feces taken from chronic renal failure(CRF) and healthy subject were cultured aerobicly. Then the isolated E. coli from CRF patients and healthy subjects was inoculated respectively into cultural medium with CRF serum and incubated whose concentration of UN, Cr and UA in medium before and after incubation was measured to observe the bacteria degrade of the above-mentioned urotoxin.
Result:
The intestinal E. coli can apparently degrade UN, Cr and UA in CRF patients which suggests that urotoxin may induce E. coli variation.