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[Clinical study on Shenning Mixture in treating IgA nephropathy].
Summary
Shenning Mixture (SNM) significantly improves IgA nephropathy treatment outcomes. SNM demonstrated higher efficacy and remission rates compared to prednisone, effectively reducing hematuria and albuminuria.
Area of Science:
- Nephrology
- Immunology
- Pharmacology
Background:
- Immunoglobulin A (IgA) nephropathy is a common glomerular disease.
- Current treatments for IgA nephropathy have limitations.
Purpose of the Study:
- To evaluate the clinical therapeutic effect of Shenning Mixture (SNM) in treating IgA nephropathy.
Main Methods:
- A randomized controlled trial comparing SNM and prednisone.
- Assessment of clinical symptoms, signs, hematuria, albuminuria, and serum IgA levels.
Main Results:
- SNM group showed a total effective rate of 97.1% and complete remission rate of 45.7%.
- Prednisone group showed a total effective rate of 37.1% and complete remission rate of 8.6%.
- SNM significantly reduced hematuria, albuminuria, and serum IgA compared to prednisone (P < 0.05, P < 0.01).
Conclusions:
- SNM exhibits significant therapeutic effects in treating IgA nephropathy.
- SNM effectively alleviates hematuria and albuminuria in IgA nephropathy patients.