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[Experimental study of daicong solution on brain M receptor in dementia model of aged rats]
Objective:
To explore the effect of Daicong Solution (DCS) on M receptor in brain of aged rat model of dementia.
Methods:
The effects of DCS on M receptor in brain of dementia model of learning and memory function hindrance were observed, the basal nuclei were ruined by destroying bilateral electrolytic method in 22-month-old rats.
Results:
Significant difference was shown in comparing the M receptor in the two groups treated by different dosages of DCS with that in the model control group (P < 0.01), significant difference also displayed in comparison of the DCS treated groups and Naofukang treated group (P < 0.01).
Conclusion:
DCS has marked effects in elevating the number and affinity of M receptor in brain of aged rat dementia model and could improve its learning and memory function, the effect was superior to that of Naofukang.