[Lipid peroxide damage in retinal ganglion cells induced by microwave]

The determination of lipid peroxide damage in the primary cultured pig retinal ganglion cells induced by microwave can provide some experience on the effect of microwave and the protection from its damage. Retinal ganglion cells were cultured in vitro and exposed to different intensities or time of microwave, and cultured for another 48 hours. The content of superoxide dismutase (SOD) and malondialdehyde (MDA) was detected. Results showed that the content of MDA was increased and SOD decreased after radiation. After 48 hours in culture, the content of MDA recovered, and SOD increased. It is concluded that microwave induced the lipid peroxide damage in primary cultured retinal ganglion cells. These damages were recoverable in certain range of intensity or time.