[Epidemiological study of airway responsiveness on the patients with asthma]

The analysis of date on 641 nuclear families with asthma declared that the sensity and specify of the airway responsiveness with Methecholone(MTCH) Challenge Test for the clinical diagnosis of asthma is 72 percent and 70 percent. The population with airway hyperresponsiveness was 6.01 times higher risk to asthma than one of negative airway responsiveness. The OR of male and female for asthma was 4.97, 5.06, respectively, and was statistically significant (P < 0.01). Moreover, the risk of asthma was been increasing with MTCH concentration was increased (i.e. degree of airway responsiveness decreased) step by step, as well showed the lineage trend between the asthma and airway responsiveness significantly (P < 0.01). The Measurement of airway responsiveness play an important role in clinic and prevent medicine.