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[Studies on synthesis and bioactivity of 2-alkenyl-4(1H)-quinolone]
1Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050.
Yao Xue Xue Bao = Acta Pharmaceutica Sinica
|April 10, 2002
Abstract:
Three 2-alkenyl-4(1H)-quinolone compounds(I-III) were synthesized by two methods. III is a new compound from Evodia rutaecarpa and was synthesized through the reaction of the aldehyde intermediate(5) with Wittig reagent. The other two compounds were synthesized for the first time. These compounds showed vasodilating and antibacteria effects in pharmacological tests.