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Updated: Aug 13, 2026

Study of Protein Dynamics via Neutron Spin Echo Spectroscopy
Published on: April 13, 2022
Review of nonlinear analysis of proteins through recurrence quantification
Joseph P Zbilut1, Paolo Sirabella, Alessandro Giuliani
1Department of Molecular Biophysics and Physiology, Rush University, Chicago, IL 60612, USA. Joseph_P_Zbilut@rush.edu
Abstract:
This review considers the use of a nonlinear signal analysis tool, recurrence quantification analysis, as a method to study sequence/structure relationships of proteins. Four broad categories are discussed: (1) a point of view involving information contained in deterministic aspects of hydrophobicity; (2) the analysis of protein hydrophobicity "singularities"; (3) time-series analysis of protein dynamics simulations; and (4) prediction of protein secondary structure.
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