Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Shaping individuality: human inheritable germ line gene modification.

M Salvi

    Theoretical Medicine and Bioethics
    |April 10, 2002
    PubMed
    Summary

    This paper examines ethical concerns of human germline gene therapy (HGLT), finding common objections lack validity. It proposes a new perspective on inheritable gene modification ethics, focusing on personal identity.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Deciphering brain metastasis in epithelial ovarian cancer: multimodal analysis and potential biomarkers.

    NPJ precision oncology·2026
    Same author

    Severe Precapillary Pulmonary Hypertension Due to Whipple Disease.

    JACC. Case reports·2025
    Same author

    A versatile 16-pole ion trap setup for investigating photophysics of biomolecular ions.

    The Review of scientific instruments·2023
    Same author

    Hyperbilirubinemia and Gilbert's syndrome in Cystic Fibrosis patients treated with elexacaftor/tezacaftor/ivacaftor.

    Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society·2023
    Same author

    Author Correction: Features of fragile people with SARS-CoV-2 infection in isolation in a COVID-19 hotel in Rome, Italy.

    European review for medical and pharmacological sciences·2022
    Same author

    Features of fragile people with SARS-CoV-2 infection in isolation in a COVID-19 hotel in Rome, Italy.

    European review for medical and pharmacological sciences·2022

    Area of Science:

    • Bioethics
    • Genetics
    • Human Germline Gene Therapy

    Background:

    • Germline gene therapy involves altering genes in reproductive cells, with implications for future generations.
    • Ethical debates often center on intergenerational responsibility, human dignity, and the moral status of embryos.

    Purpose of the Study:

    • To critically evaluate existing ethical arguments against human germline gene therapy (HGLT).
    • To propose an alternative ethical framework for assessing inheritable gene modification.

    Main Methods:

    • Analysis of common bioethical arguments concerning HGLT.
    • Development of a novel ethical perspective grounded in personal identity theory.

    Main Results:

    • Many prevailing ethical objections to HGLT are found to be insufficient.
    Keywords:
    Analytical ApproachBiomedical and Behavioral ResearchGenetics and Reproduction

    Related Experiment Videos

  • A new ethical viewpoint on inheritable genetic modification is presented.

    • Conclusions:

    • The ethical opposition to HGLT requires re-evaluation based on more robust philosophical grounds.
    • Personal identity considerations offer a promising avenue for discussing the ethics of human inheritable gene modification.