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Updated: Oct 1, 2026

Behavioral Characterization of Pentylenetetrazole-induced Seizures: Moving Beyond the Racine Scale
Published on: July 8, 2025
ECT-Induced Myoclonus
D. P. Devanand1, Harold A. Sackeim, Paolo Decina
1Department of Biological Psychiatry, New York State Psychiatric Institute and the Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York, USA.
Abstract:
We report a case of electroconvulsive therapy (ECT)-induced myoclonus which occurred postictally following every treatment and was distinguished from continuing seizure activity by electroencephalogram (EEG) recordings. Subsequent treatment with amitriptyline resulted in an isolated episode of myoclonus that did not recur when the dosage of medication was increased. Besides the clinical implications, this sequence of events raises questions about the serotonin hypothesis of antidepressant-induced myoclonus.
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