Related Experiment Video
Updated: Aug 12, 2026

08:23
A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy
Published on: November 13, 2016
Electroconvulsive Therapy in Multiple Sclerosis: A Magnetic Resonance Imaging Study of the Brain
C. Edward Coffey1, Richard D. Weiner, W. Vaughn McCall
1Departments of Psychiatry and Medicine (Neurology), Duke University Medical Center, Durham, North Carolina, USA.
Abstract:
A depressed woman with multiple sclerosis was successfully treated with electroconvulsive therapy without any adverse effects to her neurologic status. Magnetic resonance imaging of the brain was performed before and after the course of therapy and revealed no change in the white matter lesions visualized on spin-echo images.
Related Concept Videos
Brain Imaging
Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).
Electroconvulsive Therapy
Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early years,...

