Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Treatment of Phencyclidine-Associated Psychosis with ECT.

Stephen H. Dinwiddie1, Wayne C. Drevets, Dean R. Smith

  • 1Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.

Convulsive Therapy
|January 1, 1988
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Concurrent and Close Temporal Administration of Lithium and ECT.

Convulsive therapyยท1990
See all related articles

Electroconvulsive therapy (ECT) offers rapid and effective treatment for prolonged phencyclidine (PCP) psychosis unresponsive to antipsychotics. Long-term follow-up indicates sustained recovery, highlighting ECT

Area of Science:

  • Neuroscience
  • Psychiatry
  • Pharmacology

Background:

  • Phencyclidine (PCP) abuse can induce prolonged psychosis resistant to standard antipsychotic treatments.
  • Limited data exists on the long-term efficacy of treatments for PCP-associated psychosis.

Purpose of the Study:

  • To evaluate the effectiveness and long-term outcomes of electroconvulsive therapy (ECT) for PCP-associated psychosis.

Main Methods:

  • Case report of three patients with PCP-associated psychosis.
  • Patients received at least two weeks of antipsychotic medication without response.
  • Subsequent treatment with electroconvulsive therapy (ECT).

Main Results:

  • All three patients showed rapid and significant improvement following ECT.

Related Experiment Videos

  • Recovery was maintained in two patients at 14-21 months follow-up.
  • One patient relapsed due to continued PCP abuse.

    • Conclusions:

    • Electroconvulsive therapy (ECT) is a safe and effective treatment for phencyclidine (PCP)-induced psychosis.
    • ECT should be considered early for drug-associated psychoses unresponsive to antipsychotic medication.
    • Continued substance abuse can impact long-term recovery.