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Prolactin Response to Pentylenetetrazol (Cardiazol) Convulsive Therapy
Mihály Arató1, Ede Frecska, Gyöngyi Solti
1National Institute for Nervous and Mental Diseases, Budapest, Hungary.
Abstract:
Epileptic grand mal seizures as well as electroconvulsive therapy (ECT) induce a transient robust prolactin hypersecretion. Similar prolactin response has been demonstrated following pentylenetetrazol (Cardiazol)-induced seizures in two schizophrenic female patients. A slight increase in cortisol secretion but no change in thyroid stimulating hormone and growth hormone levels suggest that the prolactin response is a specific hormonal change during convulsive treatments.