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Protective Effects of Intramuscular Glycopyrrolate on Cardiac Conduction During ECT
Shashidhar M. Shettar1, Leon Grunhaus, Atul C. Pande
1Depression Program, University of Michigan Medical Center, Ann Arbor, Michigan, USA.
Abstract:
The immediate effects of electroconvulsive therapy (ECT) on cardiac conduction, with or without anticholinergic (glycopyrrolate) premedication, were systematically assessed in 19 patients. The resumption of cardiac rhythm after ECT was significantly delayed in treatments without glycopyrrolate. There was no apparent clinical impact of this phenomenon, even though some patients showed asystole of up to 6 s during nonglycopyrrolate treatments.