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Rat Brain Concentration of Fluphenazine During a Course of Electroconvulsive Shock

Iannis M. Zervas1, Lawrence B. Greenberg, Raymond F. Suckow

  • 1Department of Psychiatry and Behavioral Science, SUNY at Stony Brook, Stony Brook New York, USA.

Convulsive Therapy
|January 1, 1990
PubMed

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Electroconvulsive Therapy01:30

Electroconvulsive Therapy

Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early years,...