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[Autonomic neuropathy in somatization disorders].

Kurt Laederach-Hofmann1, Lutz Mussgay, Thomas Wilde

  • 1Zentrum für Psychobiologie und Psychosomatik der Universität Trier, Psychosomatische Fachklinik St. Franziska-Stift, Bad Kreuznach. laederach@insel.ch

Psychotherapie, Psychosomatik, Medizinische Psychologie
|April 10, 2002
PubMed
Summary

Patients with somatization disorder often exhibit autonomic dysregulation and elevated blood pressure, indicated by abnormal baroreceptor sensitivity. These findings suggest underlying organic issues may be present despite unspecific symptoms.

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Area of Science:

  • Cardiology
  • Psychiatry
  • Autonomic Nervous System Research

Background:

  • Somatization disorder is characterized by physical symptoms without a clear organic cause.
  • Autonomic nervous system (ANS) dysfunction may play a role in somatization disorder.
  • Baroreceptor sensitivity (BRS) is a key indicator of autonomic regulation.

Purpose of the Study:

  • To investigate autonomic testing abnormalities in somatization disorder patients.
  • To specifically assess central baroreceptor sensitivity in this patient group.

Main Methods:

  • Seventy-one somatization disorder patients (ICD-10, F45.0) underwent psychometric testing and autonomic regulation analysis.
  • Autonomic function was assessed using frequency spectral analysis and baroreceptor sensitivity (BRS) measurements.

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  • Patients were categorized into three groups based on BRS: low (<3.0 ms/mm Hg), normal (>9.0 ms/mm Hg), and intermediate.

    • Main Results:

    • No psychometric differences were found between extreme BRS groups.
    • Significant differences in mid-frequency spectral values were observed between groups (p < 0.05).
    • Patients with low BRS (<3.0 ms/mm Hg) exhibited significantly higher 24-hour blood pressure (p < 0.05 to 0.001).

    Conclusions:

    • Autonomic dysregulation, evidenced by abnormal BRS, is present in 17% of somatization disorder patients.
    • This dysregulation is associated with increased blood pressure.
    • The findings highlight the potential for co-occurring organic conditions in somatization disorder, even with non-specific symptoms.