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Sequential MRI in a case of Creutzfeldt-Jakob disease
G G Tribl1, G Strasser, J Zeitlhofer
1Universitätsklinik für Neurologie, Allgemeines Krankenhaus Wien, Währinger Gürtel, Vienna, Austria. Gotthard.Trivl@akh-wien.ac.at
Neuroradiology
|April 11, 2002
Abstract:
A 48-year-old man suddenly developed clinically and electroencephalographically nonspecific dementia. On MRI sequences, only diffusion-weighted images (DWI) of the cortex were unequivocally pathological. Obvious atrophy and basal ganglia signal changes appeared only 9 months after the onset. Brain biopsy confirmed Creutzfeldt-Jakob disease (CJD). In rapidly progressive dementia, we recommend DWI for early diagnosis of CJD.