Immediate reconstruction after mastectomy for breast cancer does not prolong the time to starting adjuvant chemotherapy
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Updated: Oct 1, 2026
Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
Published on: May 17, 2024
Tanir M Allweis1, Marc E Boisvert, Susan E Otero
1Center for Breast Health and the Department of Surgery, Washington Cancer Institute, Washington, DC, USA.
Background:
Immediate breast reconstruction is often performed after mastectomy for breast cancer. There has been concern that this will result in a delay in initiating chemotherapy and, as a consequence, may adversely impact survival. In this study we sought to determine whether immediate breast reconstruction affects the interval between surgery and adjuvant chemotherapy.
Methods:
A single institution retrospective analysis was made using the institutional tumor registry and chart reviews.
Results:
Forty-nine patients were identified who had undergone mastectomy with immediate reconstruction followed by adjuvant chemotherapy. They were compared with 308 patients undergoing mastectomy without reconstruction. Patients who underwent reconstruction were overall younger (46 versus 55, P <0.001), and had more advanced disease. The time to chemotherapy was significantly longer in the group receiving no reconstruction: 53 versus 41 days (P = 0.039). The type of reconstruction did not affect the time to chemotherapy.
Conclusions:
Immediate reconstruction after mastectomy does not increase the time to chemotherapy compared with mastectomy alone.
