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The Diabetes Prevention Program: recruitment methods and results.

Richard R Rubin¹, Wilfred Y Fujimoto, David G Marrero

¹DPP Coordinating Center, The Biostatistics Center, George Washington University, 61100 Executive Blvd., Suite 750, Rockville, MD 20852, USA. dppmail@biostat.bsc.gwu.edu

Controlled Clinical Trials

|April 12, 2002

Summary

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The Diabetes Prevention Program (DPP) successfully recruited participants for a trial on preventing type 2 diabetes. Effective strategies varied by demographics, highlighting the need for adaptable recruitment approaches.

Area of Science:

Clinical Trials
Public Health
Diabetes Prevention

Background:

Type 2 diabetes poses a significant public health challenge.
Impaired glucose tolerance increases the risk of developing type 2 diabetes.
The Diabetes Prevention Program (DPP) aimed to identify effective interventions.

Purpose of the Study:

To describe the recruitment methods, strategies, performance, and costs of the Diabetes Prevention Program (DPP).
To evaluate the effectiveness of different recruitment approaches in a large-scale clinical trial.

Main Methods:

The DPP employed a multicenter randomized controlled trial design.
A variety of recruitment strategies were utilized, including a stepped informed consent process.
Recruitment data were continuously monitored and analyzed to adapt strategies.

Related Experiment Videos

Main Results:

Recruitment was completed ahead of schedule, meeting diversity goals for women and racial/ethnic minorities.
Recruitment strategies varied by clinic and participant demographics (age, gender, race/ethnicity).
Recruitment costs averaged $1075 per randomized participant (excluding staff costs).

Conclusions:

Ongoing assessment and revision of recruitment strategies are crucial for trial success.
A diverse range of recruitment methods may be necessary to reach target populations.
Recruitment effectiveness and resource allocation depend on tailored demographic approaches.