Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Recoding: translational bifurcations in gene expression.

Pavel V Baranov1, Raymond F Gesteland, John F Atkins

  • 1Department of Human Genetics, University of Utah, 15N 2030E Room 7410, Salt Lake City, UT 84112-5330, USA.

Gene
|April 12, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Author Correction: Community benchmarking and evaluation of human unannotated microprotein detection by mass spectrometry based proteomics.

Nature communications·2026
Same author

Human SRD5A1 as a case of gene expression indel-resistance in triple-coding region.

Genome biology·2026
Same author

Expanding the human proteome with microproteins and peptideins.

Nature·2026
Same author

Mechanism of ribosome stalling by the AMD1 C-terminal tail arrest peptide.

Science advances·2026
Same author

An expanded reference catalog of translated open reading frames for biomedical research.

Nucleic acids research·2026
Same author

Molecular architecture and diversity of StopGo/2A translational recoding.

Proceedings of the National Academy of Sciences of the United States of America·2026

Gene expression recoding, where standard decoding is overridden, occurs in all organisms via mRNA signals. This review focuses on ribosomal frameshifting in bacteria.

Area of Science:

  • Molecular Biology
  • Genetics
  • Microbiology

Background:

  • Standard gene decoding can be altered through specific mRNA signals.
  • This phenomenon, known as recoding, is observed across diverse organisms.
  • Ribosomal frameshifting is a key mechanism of recoding, particularly in bacteria.

Purpose of the Study:

  • To review the function and distribution of recoding events in gene expression.
  • To highlight the role of ribosomal frameshifting in bacterial gene expression.

Main Methods:

  • Literature review of recoding mechanisms.
  • Analysis of mRNA-specific signals influencing translation.
  • Focus on ribosomal frameshifting in prokaryotes.

Main Results:

Related Experiment Videos

  • Recoding events override standard genetic decoding in an mRNA-specific manner.
  • Recoding is a widespread biological process, likely conserved across all life forms.
  • Ribosomal frameshifting is a significant mechanism for recoding in bacteria, impacting gene expression.

Conclusions:

  • Recoding is a fundamental aspect of gene expression regulation.
  • Understanding recoding, especially ribosomal frameshifting, is crucial for bacterial genetics.
  • Further research into recoding mechanisms can reveal novel insights into biological complexity.