Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Microscope-based techniques to study cell adhesion and migration.

Partha Roy1, Zenon Rajfur, Pawel Pomorski

  • 1Department of Cell and Developmental Biology, University of North Carolina School of Medicine, Chapel Hill, NC 27599-7090 USA.

Nature Cell Biology
|April 11, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Profilin-1 Deficiency Activates STING to Drive T Cell-Mediated Anti-Tumor Immunity in Breast Cancer.

bioRxiv : the preprint server for biology·2026
Same author

Recent advances in the development of optical chemosensors and chemodosimeters for the recognition of Hg<sup>2</sup>.

Dalton transactions (Cambridge, England : 2003)·2026
Same author

Functional regeneration of complex ballistic trauma via herbal extract and antibiotic loaded multilayered nanofibrous hydrogel scaffold.

International journal of biological macromolecules·2026
Same author

Corrigendum to "The protective effect of silver nanoparticles' on epithelial cornea cells against ultraviolet is accompanied by changes in calcium homeostasis and a decrease of the P2X7 and P2Y2 receptors" [Biomed. Pharmacother. 174 (2024) 116090].

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie·2026
Same author

Molecular insights into profilin 1-dependent regulation of cellular phosphatidylinositol (4,5)-bisphosphate.

Journal of cell science·2026
Same author

A Divergent MBL-Fold Metallo-Hydrolase (Kmh-1) from <i>Klebsiella pneumoniae</i> Confers Aztreonam Degradation and Expands the β-Lactamase Landscape.

ACS infectious diseases·2026
Same journal

An atlas of primate insular cortex reveals a signal-processing strategy in von Economo neurons.

Nature cell biology·2026
Same journal

Primate neurons with special signalling logic.

Nature cell biology·2026
Same journal

Cell surface liposome binding (CLiB) allows lipid-binding probe engineering via high-throughput screening.

Nature cell biology·2026
Same journal

Mapping the human female reproductive tract.

Nature cell biology·2026
Same journal

Learning from stem cell-based embryo models.

Nature cell biology·2026
Same journal

Why the temporal dimension matters in cellular signalling.

Nature cell biology·2026
See all related articles

Modern light microscopy offers advanced imaging to study cell adhesion and migration. These techniques analyze molecular dynamics, perturb cellular structures, and measure cell-generated forces in situ.

Area of Science:

  • Cell Biology
  • Biophysics

Background:

  • Light microscopy has advanced to include quantitative imaging.
  • These techniques allow for the perturbation of structure-function relationships in living cells.

Purpose of the Study:

  • To review the application of modern light microscopy in studying cell adhesion and migration.
  • To highlight the use of in situ techniques for analyzing molecular interactions and dynamics.
  • To discuss the perturbation of actin-based structures and measurement of cell traction forces.

Main Methods:

  • Quantitative imaging techniques in light microscopy.
  • In situ perturbation of cellular structures.
  • Measurement of cell traction forces.

Main Results:

Related Experiment Videos

  • Advanced microscopy enables detailed study of molecular interactions and dynamics during cell migration.
  • Techniques allow for localized perturbation of actin cytoskeleton.
  • Traction force microscopy quantifies forces exerted by motile cells.

Conclusions:

  • Modern light microscopy provides powerful tools for investigating cell adhesion and migration.
  • In situ analysis offers insights into the molecular mechanisms and physical forces driving cell motility.