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[Peripheral nerve regeneration under immunosuppression]
Guo-Fen Chen1, Li-Qiang Gu, Guo-Xian Pei
1Department of Orthopedic & Trauma, Nanfang Hospital, First Millitary Medical University, Guangzhou, Guangdong, P. R. China 510515.
Objective:
To discuss peripheral nerve regeneration under immunosuppression.
Methods:
Current research trends about relationship between peripheral nerve injury and immunoreaction, the experimental result of nerve regeneration after using various immunosuppressors, and the clinical findings after human allogenous hand transplantation were extensively reviewed.
Results:
Peripheral nerve regeneration was accelerated under immunosuppression.
Conclusion:
Peripheral nerve injury may induce immunoreaction, which inhibit nerve regeneration and function recovery.