Related Experiment Videos
Sudden hearing loss in chronic myelogenous leukaemia implicating the hyperviscosity syndrome
Sung Won Chae1, Jae Hoon Cho, Jang Hyuck Lee
1Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Korea University, Seoul, Korea. chaeorl@kumc.or.kr
Abstract:
Sudden sensorineural hearing loss that presents as the initial sign of haematological disease is very rare. Chronic myelogenous leukaemia has been implicated as a causative factor of sudden sensorineural hearing loss. A 49-year-old male presented with unilateral sudden sensorineural hearing loss. The patient was found to have chronic myelogenous leukaemia during a work-up for his hearing loss. We present a case of a chronic myelogenous leukaemia patient whose first manifestation was sudden sensorineural hearing loss. We presume that cochlear vessel occlusion as a result of elevated blood viscosity was responsible for this patient's hearing loss. Early onset of sudden deafness in a chronic myelogenous leukaemia patient may be due to the hyperviscosity syndrome and it may be possible to reverse hearing loss through early leukapheresis.