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Updated: Jul 17, 2026

Nuclear Transfer into Mouse Oocytes
Published on: November 30, 2006
Nuclear transfer in practice
K H Campbell1, R Alberio, J H Lee
1School of Biosciences, University of Nottingham, Leicestershire, United Kingdom. Keith.Campbell@nottingham.ac.uk
Abstract:
The technique of nuclear transfer (NT) allows the production of embryos, fetuses, and offspring from a range of embryonic, fetal, and adult derived cell types in a range of species. Successful development is dependent upon numerous factors, including type of recipient cell, source of recipient cell, method of reconstruction, activation, embryo culture, donor cell type, and donor and recipient cell cycle stages. The present review will discuss the uses of NT, the techniques presently available, and the factors affecting subsequent development.
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