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Reactivity of carboxyl groups in modified proteins
1Division of Protein Chemistry, CSIRO, Parkville (Melbourne), 3052, Victoria, Australia
Abstract:
The reactivities of carboxyl groups to carbodiimides in non-reduced, S-carboxymethyl, and S-cyanoethyl proteins have been compared. When disulphide bonds are split, a decrease in reactivity was found, relatively minor in the S-carboxymethyl derivative and almost complete loss of reactivities in the S-cyanoethyl derivative.
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