Related Experiment Video
Updated: Aug 15, 2026
09:49
Non-enzymatic, Serum-free Tissue Culture of Pre-invasive Breast Lesions for Spontaneous Generation of Mammospheres
Published on: November 8, 2014
Periductal foam cells in benign mammary dysplasia
The Journal of Pathology
|September 1, 1975
Abstract:
The morphology and associations of periductal foam cells were studied in an unselected consecutive series of 576 lesions of benign mammary dysplasia. Periductal foam cells were found to all ages in 10-1 per cent. of the lesions. Their copious foamy cytoplasm, associations with giant cells and infiltrates of periductal small round cells, ochrocytes and colostrum cells suggest that they are macrophages. Mammary epithelium was often damaged at the site of periductal foam-cell infiltration.
Related Concept Videos
01:12The Mammary Glands
The female breast is a hemispheric projection of variable size positioned anterior to the pectoralis major and serratus anterior muscles. A fascia layer composed of dense, irregular connective tissue connects it to these muscles.
Each breast features a pigmented projection known as the nipple, through which milk emerges via closely spaced openings of ducts, referred to as lactiferous ducts. Surrounding the nipple is a circular pigmented area of skin named the areola, which appears rough due to...
Each breast features a pigmented projection known as the nipple, through which milk emerges via closely spaced openings of ducts, referred to as lactiferous ducts. Surrounding the nipple is a circular pigmented area of skin named the areola, which appears rough due to...
01:24Cellular Adaptation IV: Dysplasia and Metaplasia
DysplasiaDysplasia refers to abnormal changes in the size, shape, and organization of mature cells, characterized by pleomorphism, nuclear abnormalities, and increased mitotic activity. It commonly affects epithelial tissues, including the cervix, gastrointestinal tract, respiratory mucosa, and endometrium. Although it may occur alongside hyperplasia, dysplasia is not a true adaptive response but a preneoplastic change with potential to progress to cancer.When confined above the basement...