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Ileal intussusception due to intestinal metastases from primary malignant melanoma of the lung

Mario Testini1, Senia Trabucco, Beatrice Di Venere

  • 1Institute of 2nd General Surgery, Faculty of Medicine, University of Bari, Italy.

The American Surgeon
|April 16, 2002
PubMed

Insights

Primary malignant melanoma of the lung (PMML) is a rare diagnosis. This case highlights an unusual presentation of PMML with intestinal intussusception and cerebral metastases.

Area of Science:

  • Oncology
  • Pulmonology
  • Gastroenterology

Background:

  • Primary malignant melanoma of the lung (PMML) is exceptionally rare, with stringent criteria for diagnosis.
  • Establishing a primary bronchial origin requires ruling out metastatic disease from other sites.

Observation:

  • A 44-year-old male presented with abdominal distress and a pulmonary opacity.
  • CT revealed a pulmonary nodule, cerebral metastases, and dilated intestinal loops.
  • Laparotomy identified ileal intussusception with polypoidal formations.

Findings:

  • Histological and immunohistochemical analyses confirmed melanoma in the resected intestine and brain metastases.
  • Bronchoscopy and biopsy of the pulmonary nodule revealed a neoplastic process consistent with PMML.
  • The findings support a primary lung origin despite the unusual gastrointestinal presentation.

Implications:

  • This case underscores the importance of thorough investigation for primary lung melanoma, even with atypical presentations.
  • Understanding the diagnostic criteria and histogenesis of PMML is crucial for accurate diagnosis and patient management.
  • The unusual association with intussusception warrants further consideration in the differential diagnosis of unexplained gastrointestinal and pulmonary findings.

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