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Ocular involvement in Takayasu's arteritis: response to cyclophosphamide therapy
Francisco J Rodríguez-Hurtado1, J M Sabio, J Lucena
1Service of Ophthalmology, Virgen de las Nieves, University Hospital, Granada, Spain. frodriguezhu@nexo.es
Purpose:
To report a Takayasu's arteritis (TA) case with an intense ocular involvement and the response to monthly bolus of Cyclophosphamide.
Methods:
Case report and literature review.
Results:
Cyclophosphamide was useful to improve the TA symptoms without any additional treatment and any secondary effects. When this therapy was discontinued the ocular symptoms progressed.
Conclusion:
Although no definitive therapy has been established, Cyclophosphamide intravenous bolus may be useful to improve ocular symptoms of Takayasu's Arteritis, specially in early stages. There are not adequate descriptions in the literature concerning the effect of this treatment on the ocular manifestations of TA.