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Published on: February 28, 2012
Low aspirin use in diabetics
Daad H Akbar1, Maimona M Ahmed, Aisha M Siddique
1Department of Medicine, King Abdulaziz University Hospital, PO Box 18298, Jeddah 21415, Kingdom of Saudi Arabia. daadakb@yahoo.com
Insights
Aspirin use is low among diabetic patients with cardiovascular disease or risk factors. This study found no significant differences in aspirin use between males and females, or Saudis and non-Saudis, highlighting a need for increased physician adoption.
Area of Science:
- Cardiology and Diabetes Mellitus Research
- Public Health and Preventive Medicine
Background:
- Cardiovascular disease (CVD) is a major complication in patients with diabetes mellitus.
- Aspirin is recommended for primary and secondary prevention of CVD in diabetic patients.
- Current aspirin utilization patterns in this population require investigation.
Purpose of the Study:
- To ascertain the prevalence of aspirin use in adult diabetics with established CVD or CVD risk factors.
- To examine demographic variations in aspirin use, specifically comparing males and females, and Saudi and non-Saudi populations.
Main Methods:
- Retrospective analysis of medical records from King Abdulaziz University Hospital (1998-2000).
- Data collected included patient demographics, diabetes status, CVD history, CVD risk factors (hypertension, hyperlipidemia, obesity, smoking, family history), and aspirin usage.
- Statistical analysis was performed to identify trends and significant differences.
Main Results:
- Out of 550 diabetic patients, aspirin use was significantly higher in those with CVD (63%) compared to those without (12%).
- Aspirin use was 29% in males versus 22% in females, and 24% in Saudis versus 27% in non-Saudis, with no statistically significant differences.
- Overall aspirin use was found to be low in the studied diabetic population with CVD or risk factors.
Conclusions:
- Aspirin use is suboptimal in diabetic patients with cardiovascular disease and/or risk factors.
- There are no significant demographic disparities in aspirin use based on sex or nationality.
- Increased physician emphasis on prescribing aspirin for primary and secondary CVD prevention in diabetics is warranted.
Objective:
To determine the percentage of adult diabetics with cardiovascular disease, or risk factors for cardiovascular disease who are using aspirin, and to report on any differences between males and females, or Saudis and non-Saudis.
Methods:
Medical records of diabetics seen at King Abdulaziz University Hospital during the period January 1998 through to December 2000 were analyzed. The following data were collected: patients age, sex, nationality, body mass index, duration of diabetes, history of cardiovascular disease, risk factors for cardiovascular disease (hypertension, hyperlipidemia, obesity, smoking, family history of ischemic heart disease) and aspirin use.
Results:
A total of 550 patients were studied with a mean age of 53 years and male: female ratio 1.1:1. Saudis constitute 260/550 (47%) of the study group. In patients with cardiovascular disease 110/174 (63%) were using aspirin versus 64/174 (37%) (p 0.001). In patients with one or more risk factors for cardiovascular disease but no cardiovascular disease, aspirin was used in 27/223 (12%) versus 195/223 (88%) (p 0.0001). Aspirin was used by 85/291 (29%) male versus 56/259 (22%) females (p 0.2). Sixty-three of 260 (24%) Saudis used aspirin versus 77/290 (27%) non-Saudis (p 0.7).
Conclusion:
Aspirin use is low in diabetics with cardiovascular disease and one or more risk factor of cardiovascular disease, with no significant difference between males and females, or Saudis and non-Saudis. Physicians should be encouraged to use aspirin more in diabetics for both primary and secondary prevention of cardiovascular disease.
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