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Genetic risk factors of chronic obstructive pulmonary disease
Ladina Joos1, Peter D Paré, Andrew J Sandford
1Departement Innere Medizin, Kantonsspital Basel, Switzerland. ljoos@uhbs.ch
Swiss Medical Weekly
|April 16, 2002
Abstract:
Cigarette smoking is the major risk factor for chronic obstructive pulmonary disease (COPD). However, only a minority of cigarette smokers develop symptomatic disease. Family and twin studies suggest that genetic factors also contribute to the development of COPD. We present a detailed literature review of the genes which have been investigated as potential risk factors for this disease.