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Related Experiment Videos

Genetic toxicology: web resources.

Robert R Young1

  • 1BioReliance, 14920 Broschart Road, Rockville, MD 20850, USA. byoung@bioreliance.com

Toxicology
|April 17, 2002
PubMed
Summary
This summary is machine-generated.

The internet provides extensive online resources for genetic toxicology, aiding research and regulatory compliance. These digital tools cover historical data, databases, and emerging areas like toxicogenomics.

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Area of Science:

  • Genetic toxicology, focusing on agents affecting heredity.
  • Utilizes computational tools and molecular biology advancements.

Background:

  • The internet offers a vast array of digital resources for genetic toxicology.
  • Historical data and electronic collections are reviewed.
  • Key US National Library of Medicine (NLM) resources like MEDLINE, PubMed, and TOXNET are discussed.

Purpose of the Study:

  • To review the history and electronic data collections in genetic toxicology.
  • To outline web-based resources from US government agencies (FDA, EPA, NIEHS, NTP).
  • To present regulatory web resources for testing, GLP, and electronic reporting.

Main Methods:

  • Review of NLM databases (MEDLINE, PubMed, TOXNET, CHEMIDPLUS).
  • Discussion of specific TOXNET databases (GENE-TOX, TOXLINE, HSDB, IRIS, CCIS).

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  • Identification of government agency resources and regulatory guidelines.

    • Main Results:

    • Comprehensive overview of online genetic toxicology resources.
    • Detailed examination of NLM and government agency databases.
    • Information on regulatory requirements and professional society links.

    Conclusions:

    • The internet is an invaluable tool for genetic toxicology research, education, and regulatory activities.
    • Emerging areas like toxicogenomics are increasingly supported by online resources.
    • Online platforms facilitate access to data, regulatory information, and professional development.