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Preoperative chemoembolization for unresectable hepatoblastoma
David B Tashjian1, Kevin P Moriarty, Richard A Courtney
1Division of Pediatric Surgery, Baystate Medical Center Children's Hospital, Tufts University School of Medicine, Springfield, MA, USA.
Abstract:
Complete surgical resection offers the only chance for cure in patients with hepatoblastoma (HB). Patients with unresectable lesions are given preoperative chemotherapy in an attempt to create a resectable lesion. We present a case of an 11-month-old with an unresectable stage III HB unresponsive to systemic chemotherapy. Transfemoral hepatic-artery chemoembolization resulted in a surgically resectable tumor. The patient underwent a right trisegmentectomy with complete resection of the tumor and remains tumor-free 24 months postoperatively. Salvage chemoembolization can be an effective preoperative modality to convert an unresectable tumor into a resectable one.