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Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis
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Successful treatment of Aspergillus peritonitis in a peritoneal dialysis patient

Naoko Matsumoto1, Hiroshi Shiraga, Kazuhiro Takahashi

  • 1Department of Pediatrics, Saiseikai Kurihashi Hospital, 714-6 Kurihashi-cho Kitakatsushika-gun, Saitama 349-1105, Japan. naoko@pine.memail.jp

Pediatric Nephrology (Berlin, Germany)
|April 17, 2002
PubMed

Insights

A rare fungal infection, Aspergillus peritonitis, complicates continuous ambulatory peritoneal dialysis (CAPD). Successful treatment involved catheter removal, liposomal amphotericin B, and itraconazole for a young patient.

Area of Science:

  • Mycology
  • Nephrology
  • Infectious Diseases

Background:

  • Continuous ambulatory peritoneal dialysis (CAPD) is a treatment for kidney failure.
  • Aspergillus peritonitis is a rare but serious complication of CAPD.
  • Fungal peritonitis requires prompt and aggressive management.

Observation:

  • An 8-year-old girl with 3.3 years of CAPD developed refractory fungal peritonitis.
  • The causative agent was identified as Aspergillus thermomutatus (telemorph: Neosartorya pseudofischeri).
  • This represents the second reported human case of this specific Aspergillus species.

Findings:

  • Comprehensive treatment led to successful recovery.
  • Key interventions included early CAPD catheter removal.
  • Pharmacological treatment involved liposomal amphotericin B and itraconazole.

Implications:

  • This case highlights successful management strategies for rare fungal peritonitis in CAPD patients.
  • Early diagnosis and a multi-modal treatment approach are crucial for favorable outcomes.
  • Further research into Aspergillus peritonitis in immunocompromised patients is warranted.

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