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Updated: Sep 26, 2026

Hydrodynamic Renal Pelvis Injection for Non-viral Expression of Proteins in the Kidney
Published on: January 8, 2018
[Plasma-cell granuloma of the kidney pelvis]
Elena Redondo1, Agustín Rey López, Manuel Rapariz González
1Servicios de Anatomía Patológica y Urología, Hospital de Gran Canaria Dr. Negrín, Las Palmas de Gran Canaria, España. arey@correo.hpino.rcanaria.es
Objective:
To report a rare case of plasma cell granuloma of the renal pelvis. To our knowledge, only five cases have been reported in the literature.
Methods:
Clinicopathological description of a case of plasma cell granuloma of the renal pelvis with light chain immunohistochemical study.
Results:
A young male patient with a radiologically benign mass in the right renal pelvis extending into the upper calices that caused hematuria is described. The diagnosis was suggested during the intraoperative study of the mass that was suggested by pyelotomy (conservative surgery). Immunohistochemical study confirmed the initial diagnosis.
Conclusions:
Although this condition is rare, plasma cell granuloma, an inflammatory pseudotumor, can occur in the urinary tract and should be considered in the differential diagnosis of mass lesions. Histopathological diagnosis requires a complete study of the entire tumor and the use of immunohistochemical techniques to discard plasmacytic non-Hodgkin lymphoma or neoplastic plasma cell proliferation.
Insights
This report details a rare case of plasma cell granuloma in the renal pelvis, an inflammatory pseudotumor. Early diagnosis and histopathological evaluation are crucial for managing these urinary tract mass lesions.
Area of Science:
- Uropathology
- Oncology
Background:
- Plasma cell granuloma is a rare inflammatory pseudotumor.
- Cases of renal pelvis plasma cell granuloma are exceptionally rare, with only five previously reported.
Observation:
- A young male presented with a radiologically benign mass in the right renal pelvis causing hematuria.
- The mass extended into the upper calices, necessitating intraoperative study via pyelotomy.
Findings:
- Clinicopathological description of a rare renal pelvis plasma cell granuloma.
- Light chain immunohistochemical study confirmed the diagnosis of plasma cell granuloma.
- Histopathological diagnosis requires comprehensive tumor study and immunohistochemistry to differentiate from lymphoma or neoplastic plasma cell proliferation.
Implications:
- Plasma cell granuloma should be considered in the differential diagnosis of renal pelvis mass lesions.
- Accurate histopathological diagnosis is essential to distinguish inflammatory pseudotumors from malignant conditions.
- This case highlights the importance of immunohistochemistry in diagnosing rare urinary tract pathologies.
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