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Updated: Oct 1, 2026
Microwave-assisted Intramolecular Dehydrogenative Diels-Alder Reactions for the Synthesis of Functionalized Naphthalenes/Solvatochromic Dyes
Published on: April 1, 2013
Synthesis and photochemical protein crosslinking studies of hydrophilic naphthalimides
Jianxing Zhang1, R Jeremy Woods, Philip B Brown
1Department of Chemistry & Biochemistry and Center for Drug Discovery, Baylor University, 76798-7348, Waco, TX, USA
Abstract:
A mixture of 4-alkylamino-1,8-naphthalimides has previously been reported to exhibit potential utility as a photochemical tissue-bonding reagent. In order to determine which constituents of the mixture were responsible for the observed tissue bonding and to facilitate study of the mechanism, we have synthesized each of the primary constituents of the mixture. Each naphthalimide synthesized has been demonstrated to photochemically crosslink proteins.
