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Pharmaceuticals from natural products: current trends.

Peter R Seidl1

  • 1Escola de Química, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, 21949-900, Brazil. pseidl@eq.ufrj.br

Anais Da Academia Brasileira De Ciencias
|April 18, 2002
PubMed
Summary

Natural products were once the primary medicines, but their importance shifted. Now, changing pharmaceutical strategies present new opportunities for Brazil

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Area of Science:

  • Ethnobotany
  • Medicinal Chemistry
  • Bioprospecting

Background:

  • Natural products were historically the main source of medicines until the late 19th century.
  • The significance of natural products in medicine has fluctuated with pharmaceutical industry trends.
  • Brazil's rich biodiversity offers significant potential for natural product discovery.

Purpose of the Study:

  • To explore the evolving landscape of natural product utilization in medicine.
  • To identify emerging opportunities for countries with high biodiversity, such as Brazil.
  • To outline new considerations for natural product sourcing and development.

Main Methods:

  • Historical analysis of medicinal product sources.
  • Review of current pharmaceutical industry strategies.
  • Examination of regulatory frameworks like the Convention on Biological Diversity.

Main Results:

  • Natural products dominated medicine historically, with a subsequent decline due to synthetic drug development.
  • Shifting pharmaceutical strategies are creating renewed interest in natural product-based medicines.
  • Brazil is positioned to leverage its biodiversity, but must adhere to new regulations.

Conclusions:

  • The historical reliance on natural products highlights their enduring therapeutic value.
  • New opportunities exist for bioprospecting in biodiversity-rich nations like Brazil.
  • Adherence to the Convention on Biological Diversity and integration with cosmetic/phytomedicine sectors are crucial for success.

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