Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Distributed model of collicular and cerebellar function during saccades.

Lance M Optican1, Christian Quaia

  • 1Laboratory of Sensorimotor Research, National Eye Institute, NIH, Bethesda, Maryland 20892, USA. LOptican@NIH.GOV

Annals of the New York Academy of Sciences
|April 19, 2002
PubMed
Summary

A new brain model explains rapid eye movements (saccades) using the superior colliculus and cerebellum. This distributed model suggests these brain areas encode movement goals and context, unlike older lumped models.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Neuronal Features of Visual Attention in the Mouse Superior Colliculus Depend on Learned Behavioral Relevance.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2026
Same author

High-Resolution Eye-Tracking System for Accurate Measurement of Short-Latency Ocular Following Responses: Development and Observational Study.

JMIR pediatrics and parenting·2024
Same author

Ocular-following responses to broadband visual stimuli of varying motion coherence.

Journal of vision·2024
Same author

Object recognition in primates: What can early visual areas contribute?

ArXiv·2024
Same author

Object recognition in primates: what can early visual areas contribute?

Frontiers in behavioral neuroscience·2024
Same author

Short-latency preference for faces in primate superior colliculus depends on visual cortex.

Neuron·2024

Area of Science:

  • Neuroscience
  • Systems Neuroscience
  • Computational Neuroscience

Background:

  • Classical models of rapid eye movements (saccades) utilize lumped control systems.
  • These models compute physical signal analogs but lack correspondence with anatomical and physiological data.

Purpose of the Study:

  • To propose a novel, brain-like, distributed neuromimetic model for saccade generation.
  • To elucidate the roles of the superior colliculus (SC) and cerebellum (CB) in eye movement control.

Main Methods:

  • Development of a distributed neuromimetic model integrating SC and CB functions.
  • Incorporation of target information and movement context for saccade generation.

Main Results:

  • The superior colliculus (SC) encodes the desired sensory consequence of saccades in retinotopic coordinates.

Related Experiment Videos

  • The cerebellum (CB) uses context learning and a 'pilot map' for non-computational motor control, guiding and stopping saccades.
  • No explicit desired eye movement signal is encoded; it's distributed across SC and CB activity.

    • Conclusions:

    • The proposed neuromimetic model offers a more biologically plausible explanation for saccade generation.
    • The model redefines the roles of the SC and CB, moving beyond classical lumped control system paradigms.
    • The transformation from spatial to temporal coding is implicit within the CB's velocity feedback loop.