Related Experiment Video
Updated: Aug 1, 2026

Intravascular Delivery of Biologics to the Rat Kidney
Published on: September 1, 2016
Bismuth subcitrate nephrotoxicity. A reversible cause of acute oliguric renal failure
Metin Sarikaya1, Alper Sevinc, Ramazan Ulu
1Inonu University, School of Medicine, Department of Internal Medicine, Division of Nephrology, Turgut Ozal Medical Center, Malatya, Turkey.
Abstract:
Bismuth subcitrate is a known nephrotoxic agent that may lead to acute oliguric renal failure when ingested in toxic doses. We report a 17-year-old girl who was admitted to the emergency room with complaints of nausea, vomiting, and anuria. She had taken 25 tablets containing 300 mg bismuth subcitrate (total 7.5 g). The patient was managed with hemodialysis started a week after ingestion. Bismuth subcitrate nephrotoxicity should be considered in the differential diagnosis of acute renal failure.
Related Concept Videos
Enhanced Elimination of Poison
Antidotes serve a crucial role in counteracting the effects of poison by inhibiting enzymes responsible for producing harmful drug metabolites. In some cases, these toxic metabolites can be neutralized by endogenous cosubstrates, which are maintained at specific concentrations to prevent interaction with cellular macromolecules and subsequent cell death.
Renal excretion is the...
Kidney Transplant II: Surgical Procedure
Acute Kidney Injury I: Introduction
Acute Kidney Injury II: Pathophysiology
Acute Kidney Injury III: Clinical Manifestations
Acute Kidney Injury IV: Diagnostic Studies and Prevention

