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Updated: Jul 24, 2026

A Murine Model of Ischemic Retinal Injury Induced by Transient Bilateral Common Carotid Artery Occlusion
Published on: November 12, 2020
[Occlusion of the macular branch of the central retinal artery]
Jorge Orellana1, Ricardo Garibaldi, Fernando Leiva
1Servicio de Oftalmología, Hospital Clínico San Borja-Arriarán, Santiago, Departamento de Oftalmología, Sede Centro, Facultad de Medicina, Universidad de Chile. oftajor@latinmail.com
Abstract:
We report a 54 years old female on oral anticoagulant treatment with a mitral valve disease, with a history of two transient ischemic attacks and a decreased visual acuity. She was assessed by an ophthalmologist and signs of retinal vascular disease were found. During follow up, the patient experienced an acute unilateral loss of vision in the left eye. Fundoscopy revealed an obstruction of a macular branch of central retinal artery. Aspirin was added to oral anticoagulants and one month later, the patient experienced an upper gastrointestinal bleeding. After four months of follow up, there is no recovery of left eye vision.
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