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[Transcatheter closure of atrial septal defects with the CardioSEAL occluder]

R Kaulitz1, H Bertram, M Peuster

  • 1Medizinische Hochschule Hannover Abteilung Pädiatrische Kardiologie und Pädiatrische Intensivmedizin Carl-Neuberg-Str. 1 30625 Hannover, Germany.

Zeitschrift Fur Kardiologie
|April 20, 2002
PubMed

Insights

Transcatheter closure of atrial septal defects using CardioSEAL devices is effective for various morphologies. Medium-term follow-up shows good occlusion rates and safety, supporting its use beyond typical defects.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Medical Devices

Background:

  • Limited mid- and long-term follow-up data exist for newer devices used in secundum-type atrial septal defect (ASD) closure.
  • Transcatheter closure offers a less invasive alternative to surgical repair for ASDs.

Purpose of the Study:

  • To evaluate the effectiveness and safety of transcatheter closure for various atrial septal defect morphologies using CardioSEAL and CardioSEAL-Starflex occluders.
  • To assess mid-term outcomes in patients with non-centrally located secundum-type ASDs.

Main Methods:

  • Retrospective study of 91 patients (age 1.5-71 years) who underwent transcatheter ASD closure.
  • Devices used: CardioSEAL and CardioSEAL-Starflex occluders.
  • Follow-up included transesophageal and transthoracic echocardiography, and fluoroscopy.

Main Results:

  • Overall occlusion rate increased from 66% immediately post-implantation to 86% at 24 months.
  • Patients with isolated secundum-type ASDs had a higher primary closure rate (76%) compared to those with varied morphologies.
  • No device-related thrombus, sustained atrial arrhythmia, or infective endocarditis occurred; minor device positioning issues and fatigue fractures were noted.

Conclusions:

  • Transcatheter closure with CardioSEAL double umbrella devices is effective and safe for medium-term follow-up in secundum-type ASDs.
  • The technique can be successfully applied to a range of atrial septal defect morphologies, not limited to centrally located defects.

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