Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The evolving relationship between Chlamydia pneumoniae and atherosclerosis.

Michael Dunne1

  • 1Pfizer Global Research Division, Groton, Connecticut, USA.

Current Opinion in Infectious Diseases
|April 20, 2002
PubMed
Summary

Chlamydia pneumoniae infection is linked to atherosclerosis. New diagnostic tools and research into its role in plaque development may lead to antibiotic treatments for coronary artery disease.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hydrogel-based cellular drug delivery systems as living therapeutics: Micro/nanogel design, fabrication, and controlled release.

Journal of controlled release : official journal of the Controlled Release Society·2026
Same author

Biophysical modeling identifies an optimal hybrid amoeboid-mesenchymal mechanism for maximal T cell migration speeds.

Cell reports·2026
Same author

Safety and immunogenicity of investigational tuberculosis vaccine M72/AS01<sub>E-4</sub> in people living with HIV in South Africa: an observer-blinded, randomised, controlled, phase 2 trial.

The lancet. HIV·2025
Same author

Cross-validation-based sequential design for stochastic models.

Philosophical transactions. Series A, Mathematical, physical, and engineering sciences·2025
Same author

Allied health work readiness capabilities: a qualitative comparison of graduates, supervisors, and managers' perspectives.

Journal of interprofessional care·2024
Same author

Biophysical modeling identifies an optimal hybrid amoeboid-mesenchymal mechanism for maximal T cell migration speeds.

bioRxiv : the preprint server for biology·2024

Area of Science:

  • Cardiovascular Research
  • Infectious Disease Epidemiology

Background:

  • Growing evidence links Chlamydia pneumoniae infection to atherosclerosis development.
  • Seroepidemiologic studies provide refined relative risk estimations for this association.

Purpose of the Study:

  • To summarize current understanding of Chlamydia pneumoniae's role in atherosclerosis.
  • To highlight advancements in diagnostics and pathogenesis.
  • To inform on ongoing clinical trials for antibiotic intervention.

Main Methods:

  • Review of prospective, seroepidemiologic studies.
  • Analysis of new insights into infection pathogenesis.
  • Consideration of polymerase chain reaction diagnostic advancements.

Main Results:

Related Experiment Videos

  • Established association between Chlamydia pneumoniae and atherosclerosis.
  • Improved risk estimation through recent studies.
  • Development of advanced diagnostic techniques like PCR.
  • Emerging understanding of infection's role in plaque formation.

Conclusions:

  • Chlamydia pneumoniae is a significant factor in atherosclerosis.
  • Diagnostic and pathogenic research is advancing rapidly.
  • Clinical trials are underway to evaluate antibiotic efficacy for coronary artery disease prevention and treatment.